Comparison in the middle of the Most Widely Used Ssri Drugs

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Zoloft Side Effects - Comparison in the middle of the Most Widely Used Ssri Drugs

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Drugs in the Selective Serotonin Reuptake Inhibitors (Ssri) class are widely discussed and debated for their therapeutic activity vis-à-vis side-effects in the medicine of depression and generalized anxiety disorders. Lexapro is the latest member of this class of drugs; so a comparison with Zoloft, other Ssri drug used widely in the United States, would be interesting.

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Lexapro and Zoloft have more similarities than differences in activity and side-effects. Both exert similar activity on the brain: they help verbalize the level of serotonin at a general level, so the inpatient with depression or anxiety disorders feels better.

Differences between Lexapro and Zoloft are in their respective side-effects as listed below:

Lexapro: Lexapro has a lower incidence of side-effects, most of which decrease or subside altogether in the course of treatment. Usual side-effects include: nausea, insomnia, inordinate sweating, ejaculation problems, loss of libido, somnolence and anorgasmia (inability to accomplish orgasm). There have also been instances of other side effects such as sinusitis, respiratory tract infections, flu-like symptoms and fatigue. Zoloft: Side-effects of Zoloft are similar to those of Lexapro. They include: headaches, insomnia, nausea, anxiety, nervousness, tremors, diarrhea, changing appetite, weight changes, fatigue, dry mouth and sexual dysfunctions. Occasional side-effects include: high or low blood pressure, fever, chill, allergies, irregular heartbeat/pulse rate and gastrointestinal problems.
Despite the similarities in effects and side-effects of Lexapro and Zoloft, it should be noted that gastro-intestinal problems occur more often with Zoloft, while resignation symptoms are normally more severe with Lexapro if medicine is discontinued abruptly.

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